Venomous is about a teenage boy, Locke Vinetti, who has an anger problem, but not a normal anger problem that can be treated with medication. He calls his anger "the venom". He noticed it when he was 8 years old when he bit off another kids' nose, which left him pretty much friendless. "The venom" is uncontrollable and Locke finds himself dealing with it everyday. Eventually he meets a girl named Renee, which gives him a chance to put his anger behind him, but "the venom" has no intention of being left behind.